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Perpetual pharmaceutical pearl provider

ABION is a pharmaceutical company pioneering in the development of innovative new drugs that aim to be best-in-class/first-in-class in the global market

OUR COMPANY VALUES

We are ON A BIO for the First and the Best

RESEARCH & DEVELOPMENT

In the field of oncology, ABION is developing ABN401, a targeted c-Met inhibitor for non-small cell lung cancer (NSCLC), and ABN501, a Pan-Carcinoma Claudin-3 antibody, as therapeutic options in various of cancers. Additionally, we are working on the development of ABN101, a 2nd generation Interferon-β for viral respiratory infections. These valuable assets are being developed through internationally recognized clinical processes with the aim of eventual commercialization in global markets

BEST-In-CLASS c-MET TKI

ABN401 is the tyrosine kinase inhibitor agent that targets c-Met. In cancer, c-Met triggers tumor growth and angiogenesis. Recently, it revealed that c-Met is related to a poor prognosis in cancers. Furthermore, the c-Met mutation is the largest portion of EGFR TKI resistance mechanisms. ABN401 shows a superior safety profile in the Phase I clinical trial. We aim to provide the safest targeted therapy to NSCLC patients with Met mutation.

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First-In-Class Claudin-3 Antibody

ABN501 is a novel Claudin 3(CLDN3) targeting monoclonal antibody with high specificity and strong binding affinity. Antibody-dependent cellular cytotoxicity (ADCC) activity against CLDN3-positive tumors was tested in vitro and in vivo. The pre-clinical trial is planned for 2023.

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Prophylaxis Anti-viral Inhaler Therapeutics

ABION is developing broad spectrum anti-viral inhaler drug based an 2nd generation Interferon-β. Our goal is to prevent infected patients from severity and hospitalization, improving patient convenience by stockpiling & distributing in the early phase of pandemic.

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PRESS RELEASE

February 19, 2025 in PRESS RELEASE

Abion receives approval from Ministry of Food and Drug Safety for change to phase 2 clinical trial of anticancer drug candidate ‘vabametkib’

Clinical trial of 'lazertinib' and 'vabametkib' combination: "Aiming to develop innovative new drugs"   Abion…
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December 30, 2024 in PRESS RELEASE

Abion’s c-MET targeted anticancer drug: Phase 2 change approved by FDA, Lazertinib combination kicks off

Abion announced on December 27 that the U.S. Food and Drug Administration (FDA) approved modifications…
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December 19, 2024 in PRESS RELEASE

Abion will participate in JPM-Related ‘Biotech Showcase’ and ‘Bio Partnering’ Events

"Partnering with global pharmaceutical and biotech companies offers an opportunity to build new networks"  …
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December 10, 2024 in PRESS RELEASE

[SITC 2024] Abion presents data on antibody-interferon platform for cancer treatment

HOUSTON, TX -- By Lee Han-soo/Korea Biomedical Review correspondent -- A promising new cancer treatment platform…
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November 8, 2024 in PRESS RELEASE

Abion’s ‘Vabametkib’ NSCLC Phase 1 CSR receives safety confirmation, Phase 2 progressing smoothly

Abion revealed on November 6 that it received the phase 1 Clinical Study Report (CSR)…
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October 16, 2024 in PRESS RELEASE

Abion CEO Shin Young Kee “Vabametkib and Lazertinib combination cohort filling for 3Q”

- Combination strategy unveiled at ASCO: “Safety confirmed, Cohort 2 to launch in H2 2024”…
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RECRUITMENT

ABION welcomes candidates with passion and dream-challenging spirits.

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